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J Exp Bot 57:16851696 Schafer FQ, Buettner GR (2001) Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

Further, when there is an insufficiency or total absence of GPX4, it can lead to certain types of cell death

In addition, utilizing advanced technologies like high-throughput screening, RNA sequencing, and gene-editing techniques such as clustered regularly interspaced short palindromic repeats (CRISPR) could expedite the discovery of new molecular targets for phytochemicals and help identify other bioactive compounds with stronger and more selective effects on bladder tissues

Conversely, CR displayed a more gradual decline