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Ferroptosis is intricately linked to various diseases and pathological processes, encompassing neurological conditions (e.g., Parkinsons disease, Alzheimers disease) (65, 66), cardiovascular diseases (67), and liver diseases (68)

It has been shown that the maximum desired synergistic effect of the three components in the plant mixture depends on the accurate individual selection of the three components and their precise proportions, as determined in laboratory bioassays [52]

First, transcriptional changes in Bmal1 and Hif-1 may not reflect direct regulation due to confounding factors