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While same mitochondrial problems are present in the UMNs of ALS patients with TDP-43 pathology and UMNs of TDP-43 mouse models, and since pathologies are shared at a cellular level, regardless of species, we first analyzed the metabolite profile of both healthy and diseased motor cortex to investigate whether metabolomic changes occur with respect to TDP-43 pathology

Biochem Biophys Res Commun (2018) 499(1):4451

Mihalas BP, De Iuliis GN, Redgrove KA, McLaughlin EA, Nixon B

Pour limiter les pertes de glutathion, il est aussi conseill davoir une bonne alimentation quilibre et varie qui comprend toutes les familles daliments et davoir une activit physique rgulire adapte