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Abbreviations AG: Ascorbic acid 2-glucoside DOSY: Diffusion-ordered two-dimensional nuclear magnetic resonance spectroscopy DSC: Differential scanning calorimetry FD: Freeze-dried FT-IR: Fourier-transform infrared HPLC: High-performance liquid chromatography Lid: Lidocaine NIR: Near-infrared NMR: Nuclear magnetic resonance NOESY: Nuclear Overhauser effect spectroscopy PM: Physical mixture PXRD: Powder X-ray diffraction References Abuelkheir M, Alsourani D, Al-Eyadhy A, Temsah MH, Meo SA, Alzamil F (2014) EMLA(R) cream: a pain-relieving strategy for childhood vaccination