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Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events

This pathway can be inhibited by the cell-survival signaling pathways mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) and phosphoinositide 3-kinase (PI3K)/Akt (protein kinase B), which may protect the cells against the cytotoxic effects of VPA [210]

difficile, due to weakened immune surveillance, which allows latent infections to flare

A vial stored in direct refrigerator light loses approximately 1015% more potency over 28 days compared to a foil-wrapped vial stored in darkness