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If you are increasing your dose every four weeks as per the standard schedule and experiencing severe nausea each time, ask your prescriber about extending the time at each dose to six or eight weeks

S., Palamara G., Ortelli P., Maestri R., et al

TARDBP is the gene encoding TDP-43 and leads to TDP-43 aggregates, similar to findings in nongenetic ALS, thus making it an intriguing target for intervention