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Transmission electron microscopy shows that the mitochondria of dorsal horn neurons of the spinal cord exhibit characteristic changes of ferroptosis, such as mitochondrial shrinkage and increased mitochondrial inner membrane density

However, our prior research did not thoroughly investigate the interplay among ferroptosis, inflammation, and oxidative stress, not to mention the realization of long-lasting and recyclable antioxidant treatment targeting the IVD microenvironment

E-GPx is found in plasma and extracellular fluids such as bronchoalveolar lavage fluid

Future research may focus on novel curcumin analogues that retain activity but have better solubility or stability ( 6.2 Large-scale clinical trials Manycurrent clinical studies of the role of curcumin in oral health have relatively small sample sizes or single-center designs