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Common Causes of B12 Deficiency Document the cause of B12 deficiency to support the specific code : Pernicious anemia Autoimmune destruction of stomach cells Gastrectomy or weight loss surgery Loss of intrinsic factor production Strict vegetarian diet Inadequate dietary intake Crohns disease or celiac disease Malabsorption in the small intestine Chronic pancreatitis Insufficient pancreatic enzymes Bacterial overgrowth in the small intestine Bacteria consume B12 Long-term metformin use Interferes with B12 absorption Neurologic Symptoms in B12 Deficiency B12 deficiency causes nerve damage

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Hb = 3 to 11 g/dL

The translocated cyt c hijacks histone chaperones such as suppressor of variegation, enhancer of zeste and trithorax (SET)/template-activating factor (TAF)-I, inhibiting the nucleosome assembly/disassembly activity and DNA repairing ( c has also been identified as one of the components of brainstem Lewy bodies (Wakabayashi et al., 2007) and might play as a trigger in -Syn aggregation ( c according to an in vitro study ( in vivo and whether post-translational modifications of cyt c as mentioned earlier have any effects on these moonlight functions are still unknown