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Warfarin can cause infarction Symmetrical drug related intertriginous and flexural exanthema (SDRIFE) - a symmetrical erythematous rash affecting the buttocks/natal cleft, peri-anal region or groins, usually along with one or more other flexural sites ACDR that sometimes present a long time after the drug was commenced (sometimes months or years) include: Pigmentary changes ie developing darker areas of skin, either localised or more widespread Subacute cutaneous lupus erythematosus (SCLE) - erythema and scale that is usually more widespread than compared to non-drug induced SCLE Lichenoid reactions - can be clinically indistinguishable from normal lichen planus although is frequently more severe

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Future studies can prove whether the mercapturic acid pathway is used for the excretion of GSHhematin adducts or not, in the case that these adducts are indeed formed inside the body