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These include IL-6, IL-1, and matrix metalloproteinases that disrupt tissue architecture, impair regeneration, and promote chronic inflammation

Combination of angiotensin (1-7) agonists and convalescent plasma as a new strategy to overcome angiotensin converting enzyme 2 (ACE2) inhibition for the treatment of COVID-19

It is potentially appropriate for some, in the right context, with realistic expectations, on top of an addressed foundation, with a defined cycle and a defined endpoint