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RNA sequencing of single human islet cells reveals type 2 diabetes genes

Bianchi, G., Bugianesi, E., Ronchi, M., Fabbri, A., Zoli, M., & Marchesini, G

doi:10.3390/cells90511 666. Wiesli MG, Huber MW, Weisse B, Zboray R, Kiderlen S, Gonzlez-Vzquez A, Maniura-Weber K, Rottmar M, Lackington WA

In solid tumor investigations, AMPK blocked -catenin trans-activation via activation-dependently inhibiting AKT-mediated phosphorylation of the -catenin S552 site, which in turn reduced the transcript levels of CD274 (PD-L1) in cancer cells (70)