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For instance, during chemotherapy or targeted therapy, surviving DTPs exhibit epigenetic changes characterized by increased methylation of histone H3 at lysine sites (such as H3K27 and H3K9) and dynamic remodeling of the open chromatin architecture to maintain plasticity [162, 163]

Guardians of the neonates were informed prior to screening that the data would be used for future research and signed the relevant consent forms

MDA is a relatively stable oxidizing molecule that shows similar cytotoxicity and mutagenic potential with 4-HNE, reacting with various proteins and biomolecules

The anti-tumor activity of TFPs is primarily manifested through the promotion of tumor cell apoptosis and immunostimulatory effects