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Naturally occurring antioxidants work to protect cells and tissues against the continuous production of reactive oxygen and reactive nitrogen species during normal metabolism [40]

Controls were subjects not treated with ALCAR, selected with the same inclusion and exclusion criteria as treated subjects

STK38-activated RIPK1-dependent cell death correlates with improved survival in colorectal cancer To evaluate whether STK38-mediated regulation of RIPK1-dependent cell death influences tumour progression and clinical outcomes, we analysed RNA-sequencing data from The Cancer Genome Atlas (TCGA), focusing on colon adenocarcinoma and rectal adenocarcinoma (READ), which are the tissue origins of the HT-29 cell line used in our study

Use of aflatoxin adducts as intermediate endpoints to assess the efficacy of chemopreventive interventions in animals and man