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Further downstream metabolites of the kynurenine pathway, including kynurenine itself, 3-hydroxyanthranilic acid, and quinolinic acid, have been shown to directly induce T-cell anergy, apoptosis, and regulatory T-cell differentiation (109)

Inhibition of Naja naja venom hyaluronidase: Role in the management of poisonous bite

F., Dossus, L., Dowsett, M., Eliassen, A

This modification is also referred to as the Drug Affinity Complex (DAC) and potentially supports covalent binding to albumin, significantly extending the peptides half-life and reducing proteolytic degradation