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Taken together, these findings suggest that GAA has a more pronounced effect on inducing methionine deficiency at the maternal level, while its impact on fetal methyl metabolism and postnatal phenotype appears to be limited

Risks and Side Effects While generally safe, vitamin B12 injections can have side effects or risks, such as: Mild pain, swelling, or redness at the injection site Dizziness, headache, or nausea Allergic reactions (rare) Hypokalemia (low potassium levels) in individuals with severe deficiency undergoing treatment People with allergies to cobalt or who have Lebers disease should avoid B12 injections unless specifically advised by a doctor

J.Tussing-HumphreysL.ZhanL.RajendranN.CohenJ.DionC.et al (2019)

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