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Description

It was observed that the G2019S mutation in LRRK2 results in delayed mitochondrial arrest and increased phosphorylation of the RAB10 protein (at the threonine 73 site), which in turn leads to impaired PINK1/Parkin-mediated mitophagy (Wauters et al., 2020)

This test should be used in conjunction with serum B12 and MMA and not as a sole measurement (11, 12)

The TUE Program is a rigorous and necessary part of elite sport which has overwhelming acceptance from athletes, physicians, and anti-doping stakeholders