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In T2DM, hyperglycemia and hyperinsulinemia, coupled with decreased GLUT4 expression, 480 weaken insulin signaling and diminish glucose metabolism

In negative ion mode (Figure 8D), metabolites with relatively high fold increases included Dehydroascorbate, 7,8-diaminopelargonate and DG(14:1(9Z)/16:1(9Z)/0:0), while those with relatively high fold decreases included Aloesol, 16alpha-Hydroxydehydroepiandrosterone and Glucose propionate

Exosomes secreted by mesenchymal stem cells promote endothelial cell angiogenesis by transferring miR-125a

First, metabolome profiles are determined and analytical molecular biological and biochemical analyses are performed to characterize and compare bacterial metabolomes and their correlation with the phenotype(s) of interest, in this case antibiotic-resistance or antibiotic-sensitivity