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They reported that quercetin preserves HBMECs from hypoxia and reoxygenation (H/R), which includes cell multiplication, cell migration, angiogenesis promotion, mitochondrial membrane potential injury reduction, cell apoptosis inhibition in terms of its antioxidation, and prevention of ER stress

Mol Ther 25(8):19001916 Pappa G, Lichtenberg M, Iori R, Barillari J, Bartsch H, Gerhauser C (2006) Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae

There has also been hypothesized that DNMT1 mutations could have a role in developing AML, as an increased sensitivity to DNMT1 mutations was observed in some DNMT3A mutant cellular models, but a clear conclusion has yet to be made [78]