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Description

Diener HC, Hankey GJ

The error bars in (B) and (D) represent the standard errors of the kobs values estimated separately at each inhibitor concentration, as obtained from nonlinear regression analysis

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Programmed cell death 1 ligand 1 (PD-L1), which is expressed on cancer cells, binds to the receptor PD-1 on T cells to prevent their proliferation and reduce the anti-tumor immune response, resulting in T-cell exhaustion