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In DCs, HCA2 activation reduces IL-6 levels, boosts IL-10 levels, and increases the expression of RALDH1, an enzyme responsible for converting retinol to retinoic acid (RA)

Weve entered into an agreement with Omeros Corporation to acquire and license zaltenibart (OMS906) a clinical-stage MASP-3 inhibitor with best-in-class potential across multiple rare blood and kidney disorders

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Finally, idiopathic pulmonary fibrosis (IPF) is a particularly aggressive and progressive ILD pathogenically based on an aberrant fibroproliferative wound healing response following multiple alveolar lesions, with a 5-yr survival of 30% 6,7