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These biomarkers yield valuable insights regarding i) products of lipid peroxidation, ii) products of protein modification, iii) activities of antioxidant enzymes, and iv) DNA modifications that may influence gene expression (Maon-Rossi et al., 2016)

2.11 Limited proteolysis Limited proteolysis involves controlled digestion of a protein with a protease under specific conditions to see which parts of a protein are flexible or exposed and therefore more accessible to protease, and which are protected and rigid

(2) thiol modification, where electrophilic OSCs oxidize or S-thiolate cysteine-rich enzymes in translation, respiration, and redox pathways ( S

doi:10.1111/head.14901 Haseeb ME, Mohammed HE, Yaser H, et al