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Upon reviewing the literature, DFO has been shown to reduce the level of cell death through reducing free radicals (165), and to promote wound healing and healing in diabetic patients (166), although due to the potential toxicity of DFO itself (167), the research remains only at an early stage (160)

To elucidate whether chemical chaperones leads to alleviation in mtHTT aggregation in HepG2 cells, we explored the effect of DMSO on mtHTT aggregates

The glucose uptake rate increases systematically during cleavage divisions and shows stage-specific patterns that correlate strongly with developmental competence [409, 410]

Once we limit ourselves to actual human outcomes in non-deficient adults, the evidence base becomes strikingly thin