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It was demonstrated that 1.5 mM NAC significantly increased the oocyte maturation rate, the efficiency of oocyte thalamic cell expansion, and the blastocyst rate of lone female embryos, and upregulated expression of energy metabolism-related genes (SIRT1, GGCT, MITF, and IDH3G) and downregulated expression of apoptosis- and inflammation-related genes (CASP8, FOS, MMP1, CCL2, and CXCL8)

For example , it does not dissolve in pure water, so researchers must use a suitable solvent like DMSO

doi: 10.1186/s13075-018-1609-9 130 TantohDMWuMCChuangCCChenPHTyanYSNforONet al