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Disturbed shear stress diminishes the expression of protective genes, such as Aff3ir-ORF2, which possesses anti-inflammatory and anti-atherosclerotic properties

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Pinto A, Daly A, Evans S, Almeida MF, Assoun M, Belanger-Quintana A, et al

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Biochem Pharmacol 2008

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As mentioned above, as individuals age, the secretion of the melatonin decreases, thus increasing the risk of DM complications [19]

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