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Dysregulation of iron metabolism in COVID-19-related PD Iron metabolism impairment, a significant contributor to PD [91, 92], has been extensively established in a significant fraction of COVID-19 patients in response to SARS-CoV-2 infection [93,94,95], which corresponds with the risk of severe and fatal COVID-19 illness

Cell 120: 237248 Mannava S, Grachtchouk V, Wheeler LJ, Im M, Zhuang D, Slavina EG, Mathews CK, Shewach DS, Nikiforov MA (2008) Direct role of nucleotide metabolism in CMYCdependent proliferation of melanoma cells

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Methionine can be further activated and converted into SAMe, a crucial substrate that regulates methylation