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SKU: 71852888206
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against propionic acid induced investigation on autism in Sprague Dawley rat

The receptor itself couples to multiple G proteins (Gq/11, Gi/o, G12/13, and -arrestin), and different agonists can bias signaling toward different pathways (Overlapping binding site study, 2008)

65 Further demonstrating the importance of glutaminolysis in Th17 cell differentiation, inhibition of GOT1 with aminooxyacetic acid (AOA) promoted the conversion of Th17 cells to FoxP3-expressing Tregs