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Firstly, CD206 was employed as the M2 macrophage marker to confirm macrophage polarization status using immunofluorescence staining performed under inflammatory stimuli (LPS and IFN-)

In support of this theory, it is well-established that creatine uptake into muscle, which is also sodium-dependent, can be heightened when supplementation occurs alongside the intake of high glycaemic index carbohydrates (60, 61)

The mosaic theory revisited: common molecular mechanisms coordinating diverse organ and cellular events in hypertension