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Alcohol and cardiovascular disease: still unresolved underlying mechanisms

The electrophile 4-HNE has been widely studied as a signaling molecule that stimulates the cell cycle and cell proliferation and as a cytotoxic molecule that inhibits gene expression and promotes the development of disease [19]

The VOSviewer co-occurrence network (Figure 2) revealed 157 keywords across the selected articles, with the most frequent being fatty acids, antioxidants, and epidermis, reflecting core research themes