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The multiple functions of tear fluids include: lubrication of the eyelids, formation of a smooth and even layer over the cornea and conjunctiva, providing antibacterial systems for the ocular surface and nutrients for the epithelium, act as a vehicle for the entry of polymorphonuclear leukocytes in case of injury, and washing away the toxic irritants (Lemp and Blackman 1981

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The recent SID-GBS trial has been invaluable in demonstrating the absence of justification of repeat immunoglobulin courses in severe GBS, a practice which has been widespread until now, despite previously demonstrated absence of effect of enhanced or combined immunotherapies

Early rodent studies reported that peripheral and central administration of DSIP modified slow-wave and delta sleep patterns, though subsequent research has produced variable results and the precise mechanism by which DSIP interacts with sleep architecture remains an active area of investigation