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Patents 26 (8), 907916

The best agreement in biotransformation-specific relative shifts in TW CCS N2, meas determined on precursor (+ 8.1 2 , Fig

Proc Natl Acad Sci USA 94:41554160 Rothstein JD, Martin L, Levey AI, Dykes-Hoberg M, Jin L, Wu D, Nash N, Kuncl RW (1994) Localization of neuronal and glial glutamate transporters

Istradefylline is an adenosine A2A receptor antagonist which was shown to reduce OFF-time ranging from 12 to 114 min in several trials and has been in clinical use to treat motor fluctuations in Japan for many years and more recently (2019) also received FDA approval [14, 146, 147]