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1st ed.Netherlands: Academic Press

Notably, cytokines induce significant upregulation of genes involved in IFN- signaling, NF-B regulation, antigen presentation, and free radical scavenging, further linking oxidative stress to beta-cell fragility and T1D pathogenesis ( 2.2 Experimental and epidemiological evidence linking oxidative stress to type 1 diabetes There is substantial evidence supporting a pathogenic role for oxidative stress in T1D

The formulation, enclosed in liposomes, ensures efficient nutrient absorption into the bloodstream

Being freeze-dried while being protected by a cryoprotective agent (such as trehalose), in a way that ensures that the freezing process keeps the bacteria in stasis but doesnt permanently destroy them 24 25