Unreconstituted vials should be stored refrigerated at 28C away from direct light
Neurological symptoms often develop gradually and may include: Paraesthesia : tingling or 'pins and needles' sensations, typically starting in the feet and hands Numbness : reduced sensation in the extremities, which may affect balance and coordination Burning pain : particularly in the feet, often worse at night Weakness : muscle weakness and difficulty walking Balance problems : unsteady gait and increased fall risk due to proprioceptive impairment Cognitive changes : memory problems, confusion, difficulty concentrating, and mood disturbances Haematological signs may accompany neurological symptoms and include fatigue, weakness, pallor, and shortness of breath due to megaloblastic anaemia
Migliorini, R., Sirota, P., Cohen, A
Currently, FCS is used for the analysis of the photodynamic properties of fluorescent dyes, study of translational and rotational diffusion, in various binding assays, as well as investigation of conformational fluctuations of biomolecules, and even analysis of living cells (e.g., counting fluorescence particle in vivo , probing cellular organelles, and analysis of nuclear structure) (Maiti et al., 1997
