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We argue that the molecular response to evolutionarily conserved danger stimuli may reflect common pathological mechanisms in heterogeneous critically ill patients [8]

10.1016/j.jconrel.2023.04.027 253 ZhaoL

doi:10.1038/sj.ejhg.5201320

Enhancing inhibitory signals in the pain pathway: vitamin B12 has been found to increase the effectiveness of norepinephrine and 5-hydroxytryptamine as inhibitory signals in the pain pathway, resulting in reduced pain perception