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These effects were attributed to the increase in glycine concentrations in the CNS, which contribute to the modulation of pain through the activation of glycine receptors (Morita et al

PAF C-16 has previously been shown to stimulate macrophages to produce TNF- (Dubois et al., 1989

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At the EC 0 exposure of both neonicotinoids, DEM enhanced HSP70 and VgR gene expression above control conditions as indicated by non-overlapping confidence intervals of the GAM fits and the measurements indicated by the dots on the panels in Fig