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A Cochrane review of seven different randomized clinical trials found that kava reduces anxiety compared to a placebo.[ref] The effect seems to be the largest in people with moderate to severe anxiety, but not everyone in the trial saw a benefit.[ref] Note that there are some older reports about liver toxicity with long-term use, so do your due diligence in reading up on possible side effects of kava before consuming it as a tea or supplement

In addition, most patients elect to receive medication that relaxes them during the procedure

Similarly, western blotting analysis confirmed that the expression of GPX4 in LA treated-mice was upregulated in a dose-dependent manner, compared with downregulation in FA injected-mice, although there was no significant statistical difference between two dose groups

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