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FIGURE 1 Lipid eCBs are endogenously generated from membrane phospholipids that contain arachidonic acid (AA) (Pertwee, 2010)

121,122 Getting enough sleep is also important as research has shown that sleep deprivation may increase reaction severity to allergen challenge in individuals with peanut allergy, for example

In the clinical context, PEM presents a profoundly inflammatory picture, which is not only marked by an exacerbation of all baseline ME/CFS symptoms, but often goes along with signs and symptoms of general immune stimulation

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