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Di Martino V, Verhoeven DW, Verhoeven F, Aubin F, Avouac J, Vuitton L, Liote F, Thevenot T, Wendling D (2023) Busting the myth of methotrexate chronic hepatotoxicity

doi: 10.1128/aac.03570-14 273 MessierC.GrenierD

Activation of alpha-1 leads to the (i) contraction of the iris dilator and Mullers muscles, leading to mydriasis and lid retraction, (ii) vasoconstriction causing the restriction of blood flow to the ciliary muscle, and (iii) reduced aqueous humor production [215]