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Description

These higher GSSG levels associated with lower GSH:GSSG ratios in BAL fluid (overall P = 0.004) (Figure 1A)

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Furthermore, tau aggregation can impair mitochondrial dynamics, leading to decreased mitochondrial motility and compromised mitochondrial function

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Of note, another significant source of mitochondrial NADPH is nicotinamide nucleotide transhydrogenase (NNT)

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