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Subjects in studies of six individual peptides growth hormone releasing peptide-2, ibutamoren mesylate, ipamorelin, CJC-1295, AOD-9604 and melanotan II experienced adverse events, including death

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NMs serve as emerging immunomodulatory weapons, enabling the remote manipulation of macrophage metabolism [19, 31, 40], thereby directing their polarization toward desired phenotypes for disease therapy [41], such as nanozymes combating inflammatory diseases by ROS scavenging-primed M2-like [42, 43]