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Mediators Inflamm 2014;2014:837107

Glutathione protects many thiol groups in molecules such as proteins and enzymes, so that the enzymes maintain their biological activities

Multiple viruses, including influenza virus, syncytial virus (RSV), and SARS-CoV-2, can activate the PI3K/Akt pathway to inhibit the pro-apoptotic protein B-cell lymphoma 2 (Bcl-2)-associated agonist of cell death, enhance Bcl-2 expression, thereby delaying host cell apoptosis and extending the viral replication window (Zhao et al., 2014)

As you might expect, oxidative stress can over time induce metabolic and functional changes that speed cardiovascular aging and dysfunction, and your glutathione levels declines with age, putting you at greater risk