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Lipid Peroxidation and Ferroptosis: The Role of GSH and Gpx4

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In addition, adolescents exposed to cannabis over a long period of time have a diminished response of their DA neurons to cannabis, while developing persistent cross-resistance to other substances, such as morphine, cocaine, and amphetamines 54

In view of the fact that our GST cDNA clones could provide resistance to at least 10 mM arsenate in a medium that contains only 10 mM glucose as carbon source, we feel that this mechanism is unlikely