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The downstream pathway of Nrf2, on the other hand, involves inhibitory effects on oxidative stress, inflammation and apoptosis, including but not limited to several important protein molecules, such as HO-1, SOD, MDA, TNF-, ILs, the caspase family of proteins, Bcl-2 and Bax

Under this assumption, we propose a model (Figure 9)

Yildirim C, Cevik S, Yamaner H et al (2022) Boric acid improves the behavioral, electrophysiological and histological parameters of cisplatin-induced peripheral neuropathy in rats