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The intranasal administration method has several advantages, including non-invasiveness, ease of self-administration, the ability to directly cross the BBB, rapid onset of action, and avoidance of the first-pass metabolism effect in the liver, thus improving the bioavailability of the drug

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In vivo animal studies of NAFLD were included in which berry extracts of different parts of the plant were adminis- tered and significantly improved altered biomarkers related to the pathology, such as lipid metabolism and hepatic steatosis, glucose and glycogen metabolism, and antioxidant and anti-inflammatory biomarkers