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Due to ethical limitations on extracting endothelial cells from human CC, human umbilical vein endothelial cells are commonly used because of their easy accessibility and ease of culture

bFGF, which is one of the 22 different isotypes of FGF, plays a crucial role in the wound healing process by promoting fibroblast proliferation, inducing neovascularization, and increasing the synthesis of collagenase.3033 As the topical administration of human recombinant bFGF has been shown to be effective for wound healing in clinical situations, we selected bFGF as a positive reagent in this study

If you take the peptide at 7am some days and 11am other days, you create variable metabolic conditions that make dose optimization impossible

Alanine (Ala), the smallest chiral amino acid, serves as an ideal probe for alanine-scanning mutagenesis (Figure S2)

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