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Results: There was no significant difference in demographics between the PNPLA3 types, although those with MM genotype were younger (mean age 50.9 vs 55.4 for II and 53.1 for IM) and were more likely to have Type 2 Diabetes (45% MM, 38% II, 41% IM)

Such trials should consider phenotype-stratified populationsfor example, insulin-resistant versus lean hyperandrogenic subgroupsto determine whether responses differ across the heterogeneous PCOS spectrum

Review paper: absorbable polymeric surgical sutures: chemistry, production, properties, biodegradability, and performance

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