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When using Oxycodone and Acetaminophen Tablets with CYP3A4 inducers or discontinuing CYP3A4 inhibitors, monitor patients closely at frequent intervals and consider increasing the opioid dosage if needed to maintain adequate analgesia or if symptoms of opioid withdrawal occur [see PRECAUTIONS

Die Stabilitt wurde unter Verwendung des HPLC-Verfahrens gemessen: Sule: Kromasil 100, 5 , 150 4,6 mm, mobile Phase 0,1% Trifluoressigsure in Wasser/Acetonitril (0 bis 50 Vol.-%), Gradientenelution in 25 min, Fliessgeschwindigkeit 1 ml/min, Nachweis: UV bei 214 nm

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