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Typically, intramuscular treatment for dietary vitamin B12 deficiency begins with a loading dose followed by maintenance therapy, contrasting with the steady daily doses used in oral treatment due to limited passive absorption

(PubMed) van Wijngaarden JP, Swart KM, Enneman AW, et al

So is liver, kidney, giblets, heart, and other organs

It directly stimulates anorexigenic POMC neurons and inhibits adjacent orexigenic NPY neurons in the ARC of the hypothalamus, thus promoting satiety, increasing energy expenditure, and resulting in weight loss (6)