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Fer-1, a ferroptosis inhibitor, effectively increased GSH and GPX4 levels, indicating that Fer-1 prevents ferroptosis in EBI by inhibiting neuronal lipid peroxidation (Li et al., 2021c)

However, LAC combined with clozapine was found to not significantly improve the treatment effect of schizophrenic patients who were tolerant to clozapine (73) (Studies are summarized in Table 4)