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Compared with normal cells, cancer cells are more dependent on iron and promote ferroptosis by increasing iron uptake, decreasing iron storage, limiting iron efflux and effectively killing cancer cells (24)

In short, the feature (above effect) of ferroptosis lies in the fact that the iron-dependent accumulation of lipid hydroperoxides reaches lethal levels (Stockwell et al

LIFR-alpha-dependent adipocyte signaling in obesity limits adipose expansion contributing to fatty liver disease

Rev Environ Contam Toxicol 236:193238 Mailafiya MM, Abubakar K, Chiroma SM, Danmaigoro A, Zyoud TY, Rahim EBA, Moklas MAM, Zakaria ZAB (2022) Curcuminloaded cockle shellderived calcium carbonate nanoparticles ameliorates leadinduced neurotoxicity in rats via attenuation of oxidative stress