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This approach is designed to identify potential Wnt agonists and antagonists, focusing on compounds from a comprehensive library of 5170 natural products and FDA-approved drugs

Hesperidin ameliorates pancreatic -cell dysfunction and apoptosis in streptozotocin-induced diabetic rat model

and 23 differential metabolites between the Jo-1+DM and control groups were screened, and only eight metabolites were enriched in Jo-1+DM ( Figure 4A )